He is a lecherous Furon with an Italian accent who considers cloning to be an art form, and loves earth women like Crypto did with Natalya. Unfortunately, his rival Helicobacter, an eccentric vivisectionist, keeps the prime specimens for his own experimentation.
After Crypto steals Helicobater's specimens, Endometriosis is able to take the request of creating a new body for Pox (in order to get past palace security). Now inspired, both Pox and Endometriosis wanted Helicobater dead.
After Helicobacter's death, Endometriosis celebrated his death and created a new body for Pox. Unfortunately he used the wrong mold and created "Monkey Pox". Before he could correct the error, his cloning molds were destroyed and Pox and Crypto were forced to flee.