The planet Earth is the setting for every Destroy All Humans! game in the series. It is the home planet of the Humans.
Eons ago, while humanity was still a young species, Furon sailors traveled to the insignificant planet during the Martian War. They were on shore leave and went to Earth to "let off steam". As a result, every human being alive in the present time has a strand of Furon DNA buried in their genetic code.